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Drugs & Elderly
Metformin in the diabetic elderly patient: an old, safe and effective treatment
Focus Farmacovigilanza 2016;93(3):7
Over-65 diabetics represent about half of the patients visiting general practitioners. Although diabetes pathogenesis in geriatric and young age are similar, treatment gold standards and clinical conditions are extremely variable, requiring a more individualised approach.1 In this context, a...
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Drugs & Pregnancy
Pharmacovigilance and reproductive health: the Italian contribute to the results of the EUROmediCAT project
Focus Farmacovigilanza 2016;92(1):9
EUROmediCAT – “Safety of medication use in pregnancy”, a project of the Seventh Framework Programme for Research and Technical Development funded by the European Union in the period 2011-2015, experimented integrating “traditional” registers for congenital anomalies with other already existing...
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Phytovigilance & Supplements
Herbs and drugs: friends, enemies or allies against cancer?
Focus Farmacovigilanza 2015;91(11):6
The topic of interactions between oncologic drugs and natural products has been recently at the heart of two events organized by the Project Convivio at the Oncology Unit of the Hospital of Verona, with the participation of oncological out-patients, and of another event on nutrition and cancer held...
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Drugs & Children
Drugs and gastroesophageal reflux: not always effective and with some risks
Focus Farmacovigilanza 2015;90(9):7
Paediatricians have always dedicated great attention and several diagnostic-therapeutic tools in order to tackle the gastroesophageal reflux, especially in early childhood. The most recent literature has scaled down the problem, attributing the gastroesophageal reflux to its paraphysiological...
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Drugs & Elderly
The gap between guidelines and daily practice
Focus Farmacovigilanza 2015;89(8):6
Appropriate prescription of drugs in elderly patients is one of the biggest current challenges in clinical geriatrics. As is already known, the elderly often have multiple concomitant chronic conditions (multi-morbidities), which require the simultaneous use of multiple drugs (polypharmacy), which...
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Drugs & Pregnancy
Treating migraine during pregnancy and breastfeeding
Focus Farmacovigilanza 2015;88(5):7
Migraine is a very common ailment in the reproductive age groups, with a peak prevalence of 25% between the 30th and 40th years.1 Generally, the symptoms of migraine improve during pregnancy, and return about a month after the birth. During the breastfeeding period, environmental factors, like a...
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Phytovigilance & Supplements
The rare misdeeds of green tea
Focus Farmacovigilanza 2015;87(3):6
Preparations based on green tea (Camellia sinensis) are one of the most widely consumed in the world, particularly in oriental populations. Historically, several beneficial health effects have been attributed to drinking this tea, and because of this, its potential biological activities have...
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Drugs & Children
Keep kidney damage from NSAIDs in mind
Focus Farmacovigilanza 2015;86(1):5
Non-steroidal anti-inflammatory drugs (NSAIDs) are used in paediatrics as antipyretics, anti-inflammatories and analgesics. They are products with high bioavailability, are metabolized in the liver and some (naproxen, ibuprofen, ketoprofen) partially in the kidneys as well. Their mechanism of...
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Drugs & Elderly
Use of allopurinol in the elderly
Focus Farmacovigilanza 2014;85(11):6
Allopurinol is a drug that is widely used for the treatment of hyperuricemia, which is defined by values ​​of uric acid >6.8-7 mg/dl.1 At the end of 2012 in Italy the consumption figures for allopurinol, expressed as defined daily dose (DDD), was around 185 million.2 Allopurinol is often...
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Drugs & Pregnancy
Vaccination against pandemic influenza in pregnancy
Focus Farmacovigilanza 2014;84(5):6
The risks related to influenza infection in pregnant women have been recognised for a long time.1 The pandemic of the virus A/H1N1 in the 2009-2010 season was no exception: pregnant women were at greater risk of contracting a severe form of A/H1N1 influenza than the general population, and those...
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