Perspectives

Michael D Rawlins
Focus Farmacovigilanza 2012;68(1):1
It has long been the goal of clinical pharmacologists to be able to provide the right patient, with the right drug, and at the right dose. To date this aspiration has only, to a modest extent, been achieved. Physicians select antimicrobial agents on the basis of the sensitivity of particular micro-...
Marie Lindquist
Focus Farmacovigilanza 2011;64(5):1
“You see, but you do not observe. The disctinction is clear.” Sherlock Holmes complaining to Dr Watson in A scandal in Bohemia.”Ready, next!” Old Mrs A enters. She is slightly demented, does not sleep very well, and has a failing heart, but insists on living on her own. Her medical conditions have...
Jeffrey K Aronson MA DPhil MBChB FRCP FBPharmacolS FFPM (Hon)
Focus Farmacovigilanza 2008;53(9):1
A medication error is defined as “a failure in the treatment process that leads to, or has the potential to lead to, harm to the patient” [1]. The “treatment process” starts after the decision is made to adopt treatment for symptoms or their causes, or to investigate or prevent disease or...
Gerald J. Dal Pan
Focus Farmacovigilanza 2009;58(12):1
The opinions expressed herein are those of the author, and not necessarily of the US Food and drug Administration In medicine, the term “biologic” refers to a wide range of medicinal products. These can include blood, blood components, vaccines, allergenics, recombinant therapeutic proteins,...
JM Ritter
Focus Farmacovigilanza 2010;62(12):1
Introduction Drug regulation acquired high prominence in Europe as a result of the thalidomide catastrophe. In the 1950s barbiturates were commonly used as hypnotics, and because of their narrow margin of safety due to respiratory and cardiovascular depression were predictably highly lethal when...

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